Previously, we have reported how carnosol is able to disrupt both the androgen and estrogen receptor in prostate cancer.
Carnosol is a diterpene that has been reported as a key component that contributes to the health promoting properties of rosemary extract.
More recently, we describe the single dose pharmacokinetics of carnosol in mice.
This publication represents the first in vivo pharmacokinetic study of pure carnosol in mice.
A second aspect of this project was to evaluate the potential for carnosol to inhibit key drug metabolizing enzymes using a cell free biochemical assay.
The results of this were published in the journal Toxicology and Applied Pharmacology.
The article is available here.
