Publications (Johnson Research Group)

PubMed – https://www.ncbi.nlm.nih.gov/myncbi/jeremy.johnson.1/bibliography/public

Google Scholar – https://scholar.google.com/citations?user=FZqbXKsAAAAJ&hl=en

Present – 2020

Gurgul A, Khin M, Souliya O, Sydara K, Burdette JE, Johnson JJ, Che CT. Acetogenins from the Stem of Uvaria rufa and Their Cytotoxic Activity. J Nat Prod. 2024 Feb 23;87(2):207-216. doi: 10.1021/acs.jnatprod.3c00838. PMID: 38237151

Al-Hendy A, Segars JH, Taylor HS, González F, Siblini H, Zamah M, Alkelani H, Singh B, Flores VA, Christman GM, Johnson JJ, Huang H, Zhang H.  Fibroids and unexplained infertility treatment with epigallocatechin gallate: a natural compound in green tea (FRIEND) – protocol for a randomised placebo-controlled US multicentre clinical trial of EGCG to improve fertility in women with uterine fibroids.  BMJ Open. 2024 Jan 12;14(1):e078989. doi: 10.1136/bmjopen-2023-078989. PMID: 38216200

Gurgul A, Wu Z, Han KY, Shetye G, Sydara K, Souliya O, Johnson JJ, Che CT. Polyoxygenated cyclohexene derivatives and other constituents of Uvaria rufa stem. Phytochemistry. 2023 Dec;216:113884. doi: 10.1016/j.phytochem.2023.113884. PMID: 37813133

Dahlquist A, Jandali D, Nauman MC, and Johnson JJ.  Clinical application of Momordica charantia (Bitter Melon) for reducing blood sugar in type 2 diabetes mellitus. International Journal of Nutrition – 7(4):8-26. https://doi.org/10.14302/issn.2379-7835.ijn-23-4737

Rivera Rodríguez R, Johnson JJ.  Terpenes: Modulating anti-inflammatory signaling in inflammatory bowel disease.  Pharmacol Ther. 2023 Aug;248:108456. doi: 10.1016/j.pharmthera.2023.108456. PMID: 37247693

Petukhova VZ, Aboagye SY, Ardini M, Lullo RP, Fata F, Byrne ME, Gabriele F, Martin LM, Harding LNM, Gone V, Dangi B, Lantvit DD, Nikolic D, Ippoliti R, Effantin G, Ling WL, Johnson JJ, Thatcher GRJ, Angelucci F, Williams DL, Petukhov PA. Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo. Nat Commun. 2023 Jun 22;14(1):3737. doi: 10.1038/s41467-023-39444-y. PMID: 37349300

Belcher R, Mashhad S, Dahlquist A, Johnson JJ, Dangi B, Benedetti E, Benken J, Benken ST. Characterizing the Stability of Angiotensin II in 0.9% Sodium Chloride Using High Performance Liquid Chromatography and Liquid Chromatography Tandem Mass Spectrometry. Hosp Pharm. 2024 Apr;59(2):198-201. doi: 10.1177/00185787231206525. PMID: 38450355

Siblini H, Al-Hendy A, Segars J, González F, Taylor HS, Singh B, Flaminia A, Flores VA, Christman GM, Huang H, Johnson JJ, Zhang H. Assessing the Hepatic Safety of Epigallocatechin Gallate (EGCG) in Reproductive-Aged Women. Nutrients. 2023 Jan 9;15(2):320. doi: 10.3390/nu15020320. PMID: 36678191 PMCID: PMC9861948

Gurgul A, Nauman MC, Wu Z, Shetye G, Ma R, Youn I, Souliya O, Bisson J, Johnson JJ, Che CT. Chemical constituents of the stem of Marsypopetalum modestum and their bioactivities. Nat Prod Res. 2023 Oct-Nov;37(21):3623-3630. doi: 10.1080/14786419.2022.2097229. PMID: 35819993

Nauman MC, Won JH, Petiwala SM, Vemu B, Lee H, Sverdlov M, Johnson JJ.   α-Mangostin Promotes In Vitro and In Vivo Degradation of Androgen Receptor and AR-V7 Splice Variant in Prostate Cancer Cells. Cancers (Basel). 2023 Apr 1;15(7):2118. doi: 10.3390/cancers15072118. PMID: 37046780

Nauman MC, Johnson JJ. The purple mangosteen (Garcinia mangostana): Defining the anticancer potential of selected xanthones.  Pharmacol Res. 2021 Dec 9:106032. doi: 10.1016/j.phrs.2021.106032.  PMID: 34896543

Vemu B, Tocmo R, Nauman MC, Flowers SA, Veenstra JP, Johnson JJ*.
Pharmacokinetic characterization of carnosol from rosemary (Salvia Rosmarinus) in male C57BL/6 mice and inhibition profile in human cytochrome P450 enzymes. Toxicol Appl Pharmacol. 2021. 15;431:115729. doi: 10.1016/j.taap.2021.115729.

Huang Y, Tocmo R, Nauman MC, Haughan MA, Johnson JJ*. Defining the Cholesterol Lowering Mechanism of Bergamot (Citrus bergamia) Extract in HepG2 and Caco-2 Cells. Nutrients. 2021;13(9):3156. doi: 10.3390/nu13093156.

Veenstra JP, Johnson JJ*. Rosemary (Salvia rosmarinus): Health-Promoting Benefits and Food Preservative Properties. Int J Nutr. 2021;6(4):1-10.

Gaba RC, Khabbaz RC, Muchiri RN, Morrison JD, Elkhadragy L, Totura WM, Samuelson JP, Whiteley HE, Deaton RL, Nguyen PL, Sverdlov M, Johnson JJ, van Breemen RB, Lokken RP. Conventional versus drug-eluting embolic transarterial chemoembolization with doxorubicin: comparative drug delivery, pharmacokinetics, and treatment response in a rabbit VX2 tumor model. Drug Deliv Transl Res. 2021. doi: 10.1007/s13346-021-00985-8.

Bailey HH, Johnson JJ, Lozar T, Scarlett CO, Wollmer BW, Kim K, Havinghurst T, Ahmad N. A randomized, double-blind, dose-ranging, pilot trial of piperine with resveratrol on the effects on serum levels of resveratrol. Eur J Cancer Prev. 2021;30(3):285-290. doi: 10.1097/CEJ.0000000000000621.

Veenstra JP, Vemu B, Tocmo R, Nauman MC, Johnson JJ*. Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis. Nutrients. 2021 Feb 27;13(3):773. doi: 10.3390/nu13030773.

Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ*. Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells. Free Radic Biol Med. 2021;163:102-115. doi: 10.1016/j.freeradbiomed.2020.11.018.

Tocmo R, Veenstra JP, Huang Y, Johnson JJ*. Covalent modification of proteins byplant-derived natural products: Proteomics approaches and biological impacts. Proteomics. 2021;21(3-4):e1900386. doi: 10.1002/pmic.201900386.

Nauman MC, Tocmo R, Vemu B, Veenstra JP, Johnson JJ*. Inhibition of CDK2/CyclinE1 by xanthones from the mangosteen (Garcinia mangostana): A structure-activity relationship study. Natural Products Research. 2020. 21;1-5. 

Tocmo R, Pena-Fronteras J, Calumba KF, Mendoza M, Johnson JJ*. Valorization of pomelo (Citrus grandis Osbeck) peel: A review of current utilization, phytochemistry, bioactivities and mechanisms of action. Comprehensive Reviews in Food Science and Food Safety. 2020; 19 (4): 1969-2012

Sweiss K, Vemu B, Calip GS, Wenzler E, Galvin JP, Mahmud N, Rondelli D, Johnson JJ*, Patel P. Development of a Method for Clinical Pharmacokinetic Testing to Allow for Targeted Melphalan Dosing in Multiple Myeloma Patients Undergoing Autologous Transplant. British Journal of Clinical Pharmacology. 2020 86(11):2165-2173. doi: 10.1111/bcp.14308.

2019 – 2015

Vemu B, Nauman MC, Veenstra JP, Johnson JJ*. Structure activity relationship of xanthones from mangosteen (Garcinia mangostana) for inhibition of Cyclin Dependent Kinase 4. International Journal of Nutrition. 2019;4(2):38-45.

Sweiss K, Calip GS, Johnson JJ, Rondelli D, Patel PR. Pre-transplant hemoglobin and creatinine clearance correlate with treatment free survival after autologous stem cell transplantation for multiple myeloma. Bone Marrow Transplant. 2019;54(12):2081-2087

Veenstra JP, Johnson JJ*. Oregano (Origanum vulgare) extract for food preservation and improvement in gastrointestinal health. International Journal of Nutrition. 2019;3(4):43-52

Nauman MC, Johnson JJ*. Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers. Integrative Food, Nutrition, and Metabolism. 2019; 6 (2):v1-7.

Yan M, Vemu B, Veenstra J, Petiwala SM, Johnson JJ*. Carnosol, a dietary diterpene from rosemary (Rosmarinus officinalis) activates Nrf2 leading to sestrin 2 induction in colon cells. Integrative Molecular Nutrition. 2018; 5 (4): 1-7

Petiwala SM, Li G, Petukhov P, Johnson JJ*. Carnosic acid promotes degradation of the androgen receptor and is regulated by the unfolded protein response pathway in vitro and in vivo. Carcinogenesis. 2016; 37 (8):827-38. PMID: 27267997

Li G, Petiwala SM, Yan M, Petukhov P, Johnson JJ*. Gartanin, an isoprenylated xanthone from Garcinia mangostana, is an androgen receptor degradation enhancer in prostate cancer cells. Molecular Nutrition and Food Research. 2016; 60(6):1458-69. PMID: 27019217

Petiwala SM, Johnson JJ*. Diterpenes from rosemary (Rosmarinus officinalis): Defining their potential for anti-cancer activity. Cancer Letters. 2015. 367(2):93-102 PMID: 26170168

Yan M, Li G, Petiwala SM, Johnson JJ*. Standardized rosemary (Rosmarinus officinalis) extract induces Nrf2/sestrin-2 pathway in colon cancer cells. Journal of Functional Foods. 2015. 13:137-147

2014 – 2010

Li G, Petiwala SM, Nonn L, Johnson JJ*. Inhibition of CHOP accentuates the apoptotic effect of α-mangostin from the mangosteen fruit (Garcinia mangostana) in 22Rv1 prostate cancer cells. Biochemistry and Biophysics Research Communication. 2014 ;453(1):75-80. PMID: 25261723

Ng V, Johnson JJ, Puri SC. Targeting the mTOR pathway with everolimus: implications for the management of metastatic breast cancer. Journal of Oncology Pharmacy Practice. J Oncol Pharm Pract. 2014. PMID: 24964967

Petiwala SM, Li G, Ramaiya A, Kumar A, Gill RK, Saksena S, Johnson JJ*. Pharmacokinetic characterization of mangosteen (Garcinia mangostana) fruit extract standardized to α-mangostinin C57BL/6 mice. Nutrition Research. 2014;34(4):336-45. PMID: 24774070

Petiwala SM, Berhe S, Li G, Puthenveetil AG, Rahman O, Nonn L, Johnson JJ*. Rosemary (Rosmarinus officinalis) extract modulates CHOP/GADD153 to promote androgen receptor degradation and decreases xenograft tumor growth. PLOS One. 2014 Mar 5;9(3):e89772. PMID: 24598693

Gongbo L, Petiwala SM, Pierce DM, Nonn L, Johnson JJ*. Selective modulation of endoplasmic reticulum stress markers in prostate cancer cells by a standardized mangosteen fruit extract. PLOS One 2013 Dec 18;8(12):e81572

Siddique H, Adhami VM, Parray A, Johnson JJ, Siddiqui IA, Shekhani MT, Murtaza I, Amartsumian N, Konety BR, Mukhtar H, Saleem M. S100A4 Promotes Prostate Tumorigenesis through the Activation of RAGE/NFkappaB Circuitry: Studies in Tumor cells, Human Patients and Transgenic Mouse Model. Genes Cancer. 2013; 4(5-6): 224-34.

Gongbo Li, Thomas SP, Johnson JJ*. Polyphenols from the mangosteen (Garcinia mangostana) fruit for prostate and breast cancer. Frontiers in Pharmacology. 2013;4:80. PMID: 23805102

Petiwala SM, Puthenveetil AG, Johnson JJ*. Polyphenols from the Mediterranean herb rosemary (Rosmarinus officinalis) for prostate cancer. Frontiers in Pharmacology. 2013; 4:29. PMID: 23531917

Ramaiya A, Li G, Petiwala SM, Johnson JJ*. Single dose oral pharmacokinetic profile of α- mangostin in mice. Current Drug Targets. 2012; 13: 1698-704. PMID: 23140281

Johnson JJ*, Syed DS, Rasmussen JT, Adhami V, Siddiqui IA, Kohl A, Mukhtar H. α-Mangostin, a xanthone from mangosteen fruit, inhibits CDK4 leading to G1 cell cycle arrest in prostate cancer and decreases xenograft tumor growth. Carcinogenesis. 2012; 33(2):413-9. PMID: 22159229

Johnson JJ*, Minakshi N, Siddiqui IA, Scarlett CO, Bailey HH, Muktar H, Ahmad, N. Enhancing the bioavailability of resveratrol by combining it with piperine. Molecular Nutrition and Food Research. 2011; 55(8):1169-76. PMID: 21714124

Johnson JJ*. Carnosol: a promising anti-cancer agent. Cancer Letters. 2011; 305(1):1-7. PMID: 21382660

Syed DN, Afaq F, Maddodi N, Johnson JJ, Sarafaz S, Ahmad A, Setaluri V, Mukhtar H. Inhibition of human melanoma cell growth by dietary flavonoid fisetin is associated with disruption of Wnt/β- catenin signaling and decreased Mitf levels. Journal of Investigative Dermatology. 2011;131(6):1291-9. PMID: 21346776

Johnson JJ*, Syed DS, Suh Y, Heren CR, Saleem M, Siddiqui IA, Mukhtar H. Disruption of androgen and estrogen receptor activity in prostate cancer by a novel dietary diterpene carnosol: implications for chemoprevention. Cancer Prevention Research. 2010;3:1112-23. PMID: 20736335

Suh Y, Afaq F, Khan N, Johnson JJ, Khusro FH, Mukhtar H. Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells. Carcinogenesis. 2010 Jun 8. PMID: 20530556

Johnson JJ*, Bailey H, Mukhtar H. Green tea polyphenols for prostate cancer chemoprevention: A translational perspective. Phytomedicine. 2010;17:3-13. PMID: 19959000

2009 – 2006

Saleem M, Murtaza I, Tarapore R, Suh Y, Adhami VM, Johnson JJ, Siddiqui IA, Khan N, Asim M, Hafeez BB, Shekhani MT, Li B, Mukhtar H. Lupeol Inhibits Proliferation of Human Prostate Cancer Cells by Targeting Growth Factor Receptor /β-catenin Signaling Network. Carcinogenesis. 2009;30: 808-17. PMID: 19233958

Suh Y, Afaq F, Johnson JJ, Mukhtar H. A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-κB signaling pathways. Carcinogenesis. 2009; 30: 300-7. PMID: 19037088

Johnson JJ*, Syed DN, Heren CR, Suh Y, Adhami VM, Mukhtar H. Carnosol, a dietary diterpene, displays growth inhibitory effects in human prostate cancer PC3 cells leading to G2-phase cell cycle arrest and targets the 5′-AMP-activated protein kinase (AMPK) pathway. Pharmaceutical Research. 2008. 25: 2125-34. PMID: 18286356

Saleem M, Kweon MH, Johnson JJ, Adhami VM, Elcheva I, Khan N, Bin Hafeez B, Bhat KM, Sarfaraz S, Reagan-Shaw S, Spiegelman VS, Setaluri V, Mukhtar H. S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9. Proceedings of the National Academy of Sciences USA. 2006;103:14825-30. PMID: 16990429

Pomplun M, Johnson JJ, Johnston S, Kolesar JM. Stability of a heparin-free 50% ethanol lock solution for central venous catheters. Journal of Oncology Pharmacy Practice. 2007;13:33-7. PMID: 17621565

Johnson JJ*, Mukhtar H. Curcumin for chemoprevention of colon cancer. Cancer Letters. 2007; 255(2):170-81. PMID: 17448598