In a recent paper we describe how rosemary extract, an approved food preservative in the European Union, has the potential to treat colitis in a preclinical model.
Interestingly, we found that the extract was able to target Sestrin-2 which has been reported to be overexpressed in a colitis model.
In addition, we also analyzed the pharmacokinetic properties of carnosic acid and carnosol in mice.
Our results suggest that these phytochemicals were well absorbed after oral administration.
This study suggests that rosemary may be an effective preventative agent against irritable bowel disease.
This paper was published in the journal Nutrients and is titled, “ Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.”
You can read it here https://pubmed.ncbi.nlm.nih.gov/33673488/
