Doxorubicin is a chemotherapy drug that was originally isolated from Streptomyces peucetius var. caesius in the 1970’s and has been used in a variety of cancer treatments including breast, lung, ovarian, thyroid among others cancers.
In this paper we describe how a drug eluting embolic transarterial chemoembolization can benefit the pharmacokinetic properties compared to conventional doxorubicin treatment.
This project was published in the journal Drug delivery and translational research and is titled, “Conventional versus drug-eluting embolic transarterial chemoembolization with doxorubicin: comparative drug delivery, pharmacokinetics, and treatment response in a rabbit VX2 tumor model.”
You can read the paper here https://pubmed.ncbi.nlm.nih.gov/33861419/